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What (who) is synthetase - definition

CLASS OF ENZYMES WHICH CAN FORM BONDS BETWEEN MOLECULES

Ligases; Synthetase; Sythetase; Enzymatic ligation; Amide synthases; Ligase enzyme

S-Adenosylmethionine synthetase enzyme

CLASS OF ENZYMES

Methionine adenosyltransferase; S-adenosyl-methionine synthetase; S-adenosylmethionine synthetase; User:Cboursnell/Sandbox/S/S-AdoMet synt C; S-adenosylmethionine synthetase C terminal domain; EC 2.5.1.6; ATP:L-metionin S-adenoziltransferase; S-adenosylmethionine synthetase enzyme

S-Adenosylmethionine synthetase (), also known as methionine adenosyltransferase (MAT), is an enzyme that creates S-adenosylmethionine (also known as AdoMet, SAM or SAMe) by reacting methionine (a non-polar amino acid) and ATP (the basic currency of energy).

https://en.wikipedia.org/wiki/S-Adenosylmethionine_synthetase_enzyme

Ligase

In biochemistry, a ligase is an enzyme that can catalyze the joining (ligation) of two large molecules by forming a new chemical bond. This is typically via hydrolysis of a small pendant chemical group on one of the larger molecules or the enzyme catalyzing the linking together of two compounds, e.

https://en.wikipedia.org/wiki/Ligase

Glutathione synthetase deficiency

HUMAN DISEASE

Deficiency of glutathione synthase; Deficiency of glutathione synthetase; 5-oxoprolinemia; 5-oxoprolinuria; Pyroglutamic acidemia; Pyroglutamic aciduria

Glutathione synthetase deficiency (GSD) is a rare autosomal recessive metabolic disorder that prevents the production of glutathione. Glutathione helps prevent damage to cells by neutralizing harmful molecules generated during energy production.

https://en.wikipedia.org/wiki/Glutathione_synthetase_deficiency

Wikipedia

Ligase

In biochemistry, a ligase is an enzyme that can catalyze the joining (ligation) of two large molecules by forming a new chemical bond. This is typically via hydrolysis of a small pendant chemical group on one of the larger molecules or the enzyme catalyzing the linking together of two compounds, e.g., enzymes that catalyze joining of C-O, C-S, C-N, etc. In general, a ligase catalyzes the following reaction:

Ab + C → A–C + b

or sometimes

Ab + cD → A–D + b + c + d + e + f

where the lowercase letters can signify the small, dependent groups. Ligase can join two complementary fragments of nucleic acid and repair single stranded breaks that arise in double stranded DNA during replication.

https://en.wikipedia.org/wiki/Ligase